Invention Application
US20050095234A1 Method of inducing or enhancing chondrogenesis with extracellular matrix containing GDF-5
失效
用含有GDF-5的细胞外基质诱导或增强软骨形成的方法
- Patent Title: Method of inducing or enhancing chondrogenesis with extracellular matrix containing GDF-5
- Patent Title (中): 用含有GDF-5的细胞外基质诱导或增强软骨形成的方法
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Application No.: US10982258Application Date: 2004-11-05
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Publication No.: US20050095234A1Publication Date: 2005-05-05
- Inventor: Mohammad Heidaran , Robert Spiro , Robin Daverman , LinShu Liu
- Applicant: Mohammad Heidaran , Robert Spiro , Robin Daverman , LinShu Liu
- Assignee: DEPUY SPINE, INC.
- Current Assignee: DEPUY SPINE, INC.
- Main IPC: A61K31/728
- IPC: A61K31/728 ; A61K38/17 ; A61K38/18 ; A61K38/27 ; A61K38/39 ; A61P19/00 ; C12N5/00 ; C12N5/077 ; A61K38/38 ; A61K38/47
Abstract:
A method and composition are provided for inducing or enhancing chondrogenesis in vivo or in vitro. The method is performed by exposing the cells in vitro or in vivo to an extracellular matrix comprising of type I collagen, type II collagen or a mixture of type I collagen or type II collagen and hyaluronate and further containing GDF-5.
Public/Granted literature
- US07070942B2 Method of inducing or enhancing chondrogenesis with extracellular matrix containing GDF-5 Public/Granted day:2006-07-04
Information query
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