发明申请
- 专利标题： N-(indolecarbonyl) piperazine derivatives
- 专利标题（中）： N-（吲哚羰基）哌嗪衍生物
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申请号： US11013908申请日： 2004-12-17
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公开(公告)号： US20050096330A1公开(公告)日： 2005-05-05
- 发明人: Henning Boettcher , Hartmut Greiner , Juergen Harting , Gerd Bartoszyk , Christoph Seyfried , Christoph van Amsterdam
- 申请人： Henning Boettcher , Hartmut Greiner , Juergen Harting , Gerd Bartoszyk , Christoph Seyfried , Christoph van Amsterdam
- 优先权： DE19934433.7 19990722
- 主分类号： C07D403/06
- IPC分类号： C07D403/06 ; A61K31/496 ; A61P3/04 ; A61P21/02 ; A61P25/14 ; A61P25/16 ; A61P25/18 ; A61P25/22 ; A61P25/24 ; A61P25/28 ; C07D209/04 ; C07D209/08 ; C07D209/12 ; C07D209/38 ; C07D209/40 ; C07D209/42 ; C07D209/82 ; C07D295/04 ; C07D409/12 ; C07D43/02
摘要：
The invention relates to compounds of formula (I) wherein R1, R2, R4 and R5 have the meaning given in Claim 1. Said compounds are potent 5-HT2A-antagonists and are suitable for the treatment of psychosis, schizophrenia, depression, neurological disorders, memory disorders. Parkinson's disease, amyntrophic lateral schlerosis, Alzheimer's disease, Huntington's disease, eating disorders, e.g. nervous bulimia and anorexia and premenstrual syndrome and/or for positively influencing compulsive behaviours (obsessive-compulsive disorder, OCD).
公开/授权文献
- US07084143B2 N-(indolecarbonyl) piperazine derivatives 公开/授权日：2006-08-01
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