发明申请
- 专利标题： Microfluidic chip or biomolecule crystallization
- 专利标题（中）： 微流控芯片或生物分子结晶
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申请号： US10973138申请日： 2004-10-25
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公开(公告)号： US20050112774A1公开(公告)日： 2005-05-26
- 发明人: John Gilbert , Jaishree Trikha
- 申请人： John Gilbert , Jaishree Trikha
- 主分类号： B01L3/00
- IPC分类号： B01L3/00 ; B01L3/06 ; C30B7/00
摘要：
A system for crystallizing a protein and other biomolecules comprises a flow channel for conveying a solution containing the biomolecule to be crystallized and one or more substations related to the crystallization process formed along the flow channel. The system operates by flowing a biomolecule solution through a the flow channel, then performing dialysis on a micro-scale to set crystallization conditions. After dialysis, the concentration of the biomolecule solution is changed by removing water or solvent from the biomolecule solution to promote formation of crystals in a segment of the flow channel. Formed crystals may be observed and harvested from the flow channel.
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