发明申请
- 专利标题: Spiro-cyclic compounds useful as anti-inflammatory agents
- 专利标题(中): 用作抗炎剂的螺环化合物
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申请号: US10957255申请日: 2004-10-01
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公开(公告)号: US20050119279A1公开(公告)日: 2005-06-02
- 发明人: T. G. Dhar , Edwin Iwanowicz , Michele Launay , Dominique Potin , Magali Blandine Maillet , Eric Nicolai
- 申请人: T. G. Dhar , Edwin Iwanowicz , Michele Launay , Dominique Potin , Magali Blandine Maillet , Eric Nicolai
- 主分类号: C07D498/20
- IPC分类号: C07D498/20 ; C07D513/20 ; A61K31/519 ; A61K31/4188 ; A61K31/4747 ; C07D487/12
摘要:
The present invention is directed to compounds having the formula (I): useful in treating inflammatory and immune diseases, in which K and L are independently, O or S; Q is —C(═O)— or optionally substituted C1-6alkylene; Ar is optionally-substituted aryl or heteroaryl; J1, J2, J3 and Y are selected so that ring A is a five-to-six membered optionally-substituted cycloalkenyl or heterocyclo ring having 0 to 2 nitrogen heteroatoms; R1 is N or C(R9); and R2, and R3, are as defined in the specification.
公开/授权文献
- US07199125B2 Spiro-cyclic compounds useful as anti-inflammatory agents 公开/授权日:2007-04-03
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