发明申请
US20050129612A1 Use of small molecule radioligands to discover inhibitors of amyloid-beta peptide production and for diagnostic imaging
审中-公开
使用小分子放射性配体发现淀粉样蛋白β肽生产抑制剂和诊断成像
- 专利标题： Use of small molecule radioligands to discover inhibitors of amyloid-beta peptide production and for diagnostic imaging
- 专利标题（中）： 使用小分子放射性配体发现淀粉样蛋白β肽生产抑制剂和诊断成像
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申请号： US11018331申请日： 2004-12-21
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公开(公告)号： US20050129612A1公开(公告)日： 2005-06-16
- 发明人: Robert Zaczek , Richard Olson , Dietmar Seiffert , Lorin Thompson
- 申请人： Robert Zaczek , Richard Olson , Dietmar Seiffert , Lorin Thompson
- 主分类号： A61K51/08
- IPC分类号： A61K51/08 ; A61K51/00
摘要：
This invention relates to a method of using radiolabelled and/or radiopharmaceutical small molecule inhibitors of beta-amyloid peptide production for the diagnosis of neurological and other disorders involving APP processing and beta-amyloid production. Furthermore, radiolabelled small molecule inhibitors identified by the methods of the present invention would be useful in the diagnosis of neurological disorders, such as Alzheimer's disease, which involve elevated levels of Aβ peptides.
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