发明申请
US20050142192A1 Oral administration of [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)alkyl] phosphonic acid and derivatives
审中-公开
口服给予[2-(8,9-二氧代-2,6-二氮杂双环[5.2.0]壬-1(7) - 烯-2-基)烷基]膦酸及其衍生物
- 专利标题: Oral administration of [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)alkyl] phosphonic acid and derivatives
- 专利标题(中): 口服给予[2-(8,9-二氧代-2,6-二氮杂双环[5.2.0]壬-1(7) - 烯-2-基)烷基]膦酸及其衍生物
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申请号: US10961871申请日: 2004-10-08
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公开(公告)号: US20050142192A1公开(公告)日: 2005-06-30
- 发明人: Eric Benjamin , William Cloud , Muhammad Ashraf , Mohammed Islam , Michael Brandt , Gerald Tremblay
- 申请人: Eric Benjamin , William Cloud , Muhammad Ashraf , Mohammed Islam , Michael Brandt , Gerald Tremblay
- 申请人地址: US NJ Madison
- 专利权人: Wyeth
- 当前专利权人: Wyeth
- 当前专利权人地址: US NJ Madison
- 主分类号: A61K31/55
- IPC分类号: A61K31/55 ; A61K31/675 ; A61K9/20
摘要:
Solid, pharmaceutical dosage forms of [2-(8,9-dioxo-2,6-diazabicyclo [5.2.0]non-1(7)-en-2-yl)alkyl]phosphonic acid and derivatives thereof are disclosed. In addition, methods of use are disclosed for the treatment, inter alia, of cerebral vascular disorders, anxiety disorders; mood disorders; schizophrenia; schizophreniform disorder; schizoaffective disorder; cognitive impairment; chronic neurodegenerative disorders; inflammatory diseases; fibromyalgia; complications from herpes zoster; prevention of tolerance to opiate analgesia; withdrawal symptoms from addictive drugs; and pain.
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