发明申请
- 专利标题： Tissue plasminogen activator-like protease
- 专利标题（中）： 组织纤溶酶原激活物样蛋白酶
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申请号： US11035988申请日： 2005-01-18
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公开(公告)号： US20050164366A1公开(公告)日： 2005-07-28
- 发明人: Paul Moore , Steven Ruben , Reinhard Ebner
- 申请人： Paul Moore , Steven Ruben , Reinhard Ebner
- 申请人地址： US MD Rockville
- 专利权人： Human Genome Sciences, Inc.
- 当前专利权人： Human Genome Sciences, Inc.
- 当前专利权人地址： US MD Rockville
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K38/00 ; A61P7/02 ; A61P9/00 ; C12N1/21 ; C12N5/10 ; C12N9/64 ; C12N15/55 ; C07H21/04 ; C07K16/40
摘要：
The present invention relates to a novel t-PALP protein which is a member of the serine protease family. In particular, isolated nucleic acid molecules are provided encoding the human t-PALP protein. t-PALP polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of t-PALP activity. Also provided are diagnostic methods for detecting circulatory system-related disorders and therapeutic methods for treating circulatory system-related disorders.
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