发明申请
- 专利标题： Enhanced inserted yellow fluorescence protein and its application
- 专利标题（中）： 增强插入黄色荧光蛋白及其应用
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申请号： US10506925申请日： 2003-03-08
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公开(公告)号： US20050170428A1公开(公告)日： 2005-08-04
- 发明人: Dong-Seung Seen , Jac-Yong Park , Young-Shik Choi , Eun-Wook Choi , Ho-Sun Son , Neon-C. Jung , Anthony Kang , Ji-Ung Maeng , Kyung-Jin Kim , Jung-Hee Shin
- 申请人： Dong-Seung Seen , Jac-Yong Park , Young-Shik Choi , Eun-Wook Choi , Ho-Sun Son , Neon-C. Jung , Anthony Kang , Ji-Ung Maeng , Kyung-Jin Kim , Jung-Hee Shin
- 优先权： KR10-2002-0012409 20020308; KR10-2002-0015217 20020321; KR10-2002-0015219 20020321
- 国际申请： PCT/KR03/00455 WO 20030308
- 主分类号： C07K14/435
- IPC分类号： C07K14/435 ; G01N33/53 ; A01K67/00
摘要：
Disclosed are mutated genes for green fluorescence proteins and enhanced inserted YFPs expressed therefrom. The mutant proteins not only maintain their fluorescence even at 37° C., but also exhibit about 20 times stronger fluorescence intensities in comparison to the conventional fluorescence proteins. Accordingly, the mutant fluorescence proteins of the present invention can be used as biosensors for detecting and analyzing the bioactivities of desired materials.
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