发明申请
- 专利标题: Deimmunized binding molecules to CD3
- 专利标题(中): 去免疫结合分子与CD3
-
申请号: US10966406申请日: 2004-10-15
-
公开(公告)号: US20050176028A1公开(公告)日: 2005-08-11
- 发明人: Robert Hofmeister , Christian Itin , Francis Carr , Patrick Bauerle , Anita Hamilton , Stephen Williams
- 申请人: Robert Hofmeister , Christian Itin , Francis Carr , Patrick Bauerle , Anita Hamilton , Stephen Williams
- 优先权: EPEP03023580.8 20031016
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; C07K16/46 ; C12Q1/68 ; C07H21/04 ; C07K14/74 ; G01N33/53 ; G01N33/567
摘要:
The invention provides CD3 specific binding molecules and nucleic acid sequences encoding said CD3 specific binding molecules. Further aspects of the invention are vectors and host cells comprising said nucleic acid sequence, a process for the production of the construct of the invention and compositions comprising said construct. The invention also provides the use of said constructs for the preparation of pharmacutical compositions for the treatment of particular diseases, a method for the treatment of particular diseases and a kit comprising the binding construct of the invention.
信息查询