发明申请
- 专利标题： Modulators of acetylcholine receptors
- 专利标题（中）： 乙酰胆碱受体的调节剂
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申请号： US10500516申请日： 2002-07-29
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公开(公告)号： US20050182088A1公开(公告)日： 2005-08-18
- 发明人: Peter Astles , Stephen Baker , Rowena Cube , Jose Martinez-Perez , Ana Mateo Herranz , Jean Vernier , Colin Dell , Sonia Gutierrez , Lourdes Prieto , Martine Keenan , Adam Sanderson , Colin Smith
- 申请人： Peter Astles , Stephen Baker , Rowena Cube , Jose Martinez-Perez , Ana Mateo Herranz , Jean Vernier , Colin Dell , Sonia Gutierrez , Lourdes Prieto , Martine Keenan , Adam Sanderson , Colin Smith
- 国际申请： PCT/US02/21296 WO 20020729
- 主分类号： A61K31/46
- IPC分类号： A61K31/46 ; A61K31/55 ; C07D451/04 ; C07D451/14 ; C07D471/02 ; A61K31/4745 ; C07D453/04
摘要：
The present invention relates to compounds that modulate neurotransmission by promoting the release of neurotransmitters such as acetylcholine, dopamine and norepinephrine. More particularly, the present invention relates to thio-bridged aryl compounds that are capable of modulating acetylcholine receptors and pharmaceutical compositions comprising such compounds. The compounds disclosed are useful for the treatment of dysfunctions of the central and autonomic nervous systems.
公开/授权文献
- US07148236B2 Modulators of acetylcholine receptors 公开/授权日：2006-12-12
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