发明申请
US20050187187A1 Carboxyl-reduced derivatives of chondroitin sulfate, preparation thereof, use thereof as a medicinal product and the pharmaceutical compositions containing them
审中-公开
硫酸软骨素的羧基还原的衍生物，其制备，其作为药用产品的用途和含有它们的药物组合物
- 专利标题： Carboxyl-reduced derivatives of chondroitin sulfate, preparation thereof, use thereof as a medicinal product and the pharmaceutical compositions containing them
- 专利标题（中）： 硫酸软骨素的羧基还原的衍生物，其制备，其作为药用产品的用途和含有它们的药物组合物
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申请号： US11016175申请日： 2004-12-17
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公开(公告)号： US20050187187A1公开(公告)日： 2005-08-25
- 发明人: Wolfgang Ulmer , Christian Viskov , Philippe Hubert
- 申请人： Wolfgang Ulmer , Christian Viskov , Philippe Hubert
- 申请人地址： FR Antony
- 专利权人： Aventis Pharmas S.A.
- 当前专利权人： Aventis Pharmas S.A.
- 当前专利权人地址： FR Antony
- 优先权： FR0314988 20031219
- 主分类号： A61K31/737
- IPC分类号： A61K31/737 ; C08B37/00
摘要：
The present invention relates to the carboxyl-reduced and chemoselectively O-sulfated derivatives of chondroitin sulfate of formula (I): in which R1, R2, R3 and R4 are H or SO3M, n is an integer of between 0 and 200, M is an alkali metal, isolated or as mixtures, to the diastereoisomers thereof, to the process for the preparation thereof, to the uses thereof as a medicinal product and to the pharmaceutical compositions containing them.
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