摘要:
The invention relates to a method of analyzing spectral data for the selection of a calibration model, relating spectra of a substance to a physical or chemical parameter of the substance, over a predetermined range of the physical or chemical parameter, comprising the steps: a) capturing spectral data of the substance with respective values of the physical or chemical parameter over the predetermined range, b) creating a plurality of calibration models using the captured spectral data in dependence upon the values of the physical or chemical parameter based on the calibration data using statistical resampling methods, c) calculating tolerance intervals of the results at each reference level for each calibration model, and d) displaying the tolerance intervals at each reference level over the predetermined range for each calibration model. In this way, a possibility for analyzing spectra data is provided which is useful in spectroscopic applications for automated calibration model selection and makes analytical interpretation and evaluation easier and more accurate.
摘要:
The invention relates to biotinylated low molecular weight heparins comprising constituent polysaccharides having at their reducing ends at least one covalent bond with biotin or a biotin derivative, and also to the process for preparing them, to pharmaceutical compositions containing them and to their therapeutic use.
摘要:
The invention relates to biotinylated heparins comprising constituent polysaccharides having at their reducing ends at least one covalent bond with biotin or a biotin derivative, and also to the process for preparing them, to pharmaceutical compositions containing them and to their therapeutic use. The biotinylated polysaccharides are of the formula (I) with the variables as defined herein.
摘要:
The present invention relates to the carboxyl-reduced derivatives of dermatan sulfate of formula (I): in which R1, R2, R3 or R4 represents H or SO3M, n is an integer of between 0 and 150, M is an alkali metal, isolated or as mixtures, to the diastereoisomers thereof, to the process for the preparation thereof, to the uses thereof as a medicinal product and to the pharmaceutical compositions containing them.
摘要:
The invention relates to a method of analyzing spectral data for the selection of a calibration model, relating spectra of a substance to a physical or chemical parameter of the substance, over a predetermined range of the physical or chemical parameter, comprising the steps: a) capturing spectral data of the substance with respective values of the physical or chemical parameter over the predetermined range, b) creating a plurality of calibration models using the captured spectral data in dependence upon the values of the physical or chemical parameter based on the calibration data using statistical resampling methods, c) calculating tolerance intervals of the results at each reference level for each calibration model, and d) displaying the tolerance intervals at each reference level over the predetermined range for each calibration model. In this way, a possibility for analyzing spectra data is provided which is useful in spectroscopic applications for automated calibration model selection and makes analytical interpretation and evaluation easier and more accurate.
摘要:
The device includes a main receptacle (1) having an overflow pipe (2) and a secondary receptacle (9) mounted so as to be freely movable in the vertical direction inside the main receptacle (1). The inner space of the secondary receptacle (9) communicates with a drainage pipe (8) for fluid lost by the hydraulic installation. The secondary receptacle (9) floats in the fluid contained in the main receptacle (1). The immersion level of the secondary receptacle (9) increases, depending on the amount of lost fluid received by the secondary receptacle (9), and the supply of fluid from the main receptacle (1) is caused by the immersion of the secondary receptacle (9).
摘要:
A method of and apparatus for executing a family of instructions provides synchronization of processes in a multiprocessing system. Representations of processes awaiting data (information units) such as the completion of an asynchronous operation or the availability of a resource are stored in a memory in a first queue and representations of information units available to processes are stored in memory in a second queue. Transfer of information units between processes is controlled by data elements known as "semaphores" stored in the memory. Each semaphore contains a field having a numerical value identifying which of the two different kinds of queues is present. When a P instruction is executed by a process indicating that the process requires data in order to continue operating or a V instruction is executed indicating that an information unit is available for transfer to another process, a semaphore is addresses and its field tested to determine whether processes or information units are available to enable the information transfer between processes to be effected. Once the information transfer is completed, the field of the addressed semaphore is up-dated.
摘要:
An information structure, or semaphore, serves as a signalling mechanism in process synchronization to connect a process and a non-simultaneously occurring event or resource. The semaphore is a data structure which stores representations of processes awaiting particular events or alternatively stores representations of events awaiting processes. Semaphore data structures are developed in two storage areas. First and second groups of process links are stored in the first storage area to establish, respectively, a first queue of processes ready to operate and a second queue, associated with the semaphore structure, of processes awaiting occurrences of a first particular event prior to being ready to operate. In the second storage area are stored first and second groups of message links to establish respectively a first queue, associated with a semaphore structure, representing second particular events and a second queue of unused links. A signal is generated in response to operation of a first process to denote the occurrence of a first event. In response to the signal, the first event is associated with a process represented by a process link in the second queue of process links when the first event is the first particular event. When no queue has a process link identifying a process awaiting the occurrence of the first event, a representation of the first event occurrence is stored in a message link of the second queue of message links to be transferred to the first queue of message links. Process and event occurrence representations are thus transferred among the process and event queues during synchronization that takes place between the processes and events.
摘要:
The present invention relates to the carboxyl-reduced and chemoselectively O-sulfated derivatives of chondroitin sulfate of formula (I): in which R1, R2, R3 and R4 are H or SO3M, n is an integer of between 0 and 200, M is an alkali metal, isolated or as mixtures, to the diastereoisomers thereof, to the process for the preparation thereof, to the uses thereof as a medicinal product and to the pharmaceutical compositions containing them.
摘要:
Heterocyclylalkylpiperidine derivatives of general formula (I) in their enantiomeric or diastereoisomeric forms or mixtures of these forms, and/or, where appropriate, in their syn or anti form or a mixture thereof, as well as any salt thereof.