发明申请
- 专利标题： Compounds and compositions as protein kinase inhibitors
- 专利标题（中）： 化合物和组合物作为蛋白激酶抑制剂
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申请号： US10961646申请日： 2004-10-08
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公开(公告)号： US20050187230A1公开(公告)日： 2005-08-25
- 发明人: Qiang Ding , Yongping Xie , Nathanael Gray , Shuli You , Greg Chopiuk , Jiqing Jiang , Yi Liu , Ruo Steensma , Xing Wang , Taebo Sim
- 申请人： Qiang Ding , Yongping Xie , Nathanael Gray , Shuli You , Greg Chopiuk , Jiqing Jiang , Yi Liu , Ruo Steensma , Xing Wang , Taebo Sim
- 申请人地址： BM Hamilton
- 专利权人： IRM LLC
- 当前专利权人： IRM LLC
- 当前专利权人地址： BM Hamilton
- 主分类号： A61K
- IPC分类号： A61K20060101 ; A61K31/44 ; A61K31/47 ; A61K31/4706 ; A61K31/4745 ; A61K31/519 ; C07D215/16 ; C07D471/00 ; C07D471/02
摘要：
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, BCR-Abl, CSK, JNK1, JNK2, PDGF-R, p38, p70S6K, TGFβ, SRC, EGFR, c-Kit, trkB, FGFR3, Fes, Lck, Syk, RAF, MKK4, MKK6 and SAPK2β kinases.
公开/授权文献
- US07449582B2 Compounds and compositions as protein kinase inhibitors 公开/授权日：2008-11-11
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