发明申请
US20050196403A1 Inducing cellular immune responses to p53 using peptide and nucleic acid compositions
审中-公开
使用肽和核酸组合物诱导对p53的细胞免疫应答
- 专利标题： Inducing cellular immune responses to p53 using peptide and nucleic acid compositions
- 专利标题（中）： 使用肽和核酸组合物诱导对p53的细胞免疫应答
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申请号： US11051411申请日： 2005-02-07
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公开(公告)号： US20050196403A1公开(公告)日： 2005-09-08
- 发明人: John Fikes , Alessandro Sette , John Sidney , Scott Southwood , Robert Chesnut , Esteban Celis , Elissa Keogh
- 申请人： John Fikes , Alessandro Sette , John Sidney , Scott Southwood , Robert Chesnut , Esteban Celis , Elissa Keogh
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K39/00 ; C07K14/47 ; C07K14/74
摘要：
This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare p53 epitopes, and to develop epitope-based vaccines directed towards p53-bearing tumors. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of cancer.
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