发明申请
US20050196843A1 Recombinant cell clones having increased stability and methods of making and using the same
有权
具有增加的稳定性的重组细胞克隆及其制备和使用方法
- 专利标题： Recombinant cell clones having increased stability and methods of making and using the same
- 专利标题（中）： 具有增加的稳定性的重组细胞克隆及其制备和使用方法
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申请号： US11123362申请日： 2005-05-06
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公开(公告)号： US20050196843A1公开(公告)日： 2005-09-08
- 发明人: Manfred Reiter , Wolfgang Mundt , Friedrich Dorner
- 申请人： Manfred Reiter , Wolfgang Mundt , Friedrich Dorner
- 申请人地址： AT Vienna US CA Irvine
- 专利权人： Baxter Aktiengesellschaft,Baxter Healthcare Corporation
- 当前专利权人： Baxter Aktiengesellschaft,Baxter Healthcare Corporation
- 当前专利权人地址： AT Vienna US CA Irvine
- 优先权： ATA1073/97 19970620
- 主分类号： C12N5/00
- IPC分类号： C12N5/00 ; C12N5/08 ; C12N5/06 ; C07H21/04 ; C07K14/755
摘要：
Disclosed are a stable recombinant cell clones which are stable in serum- and protein-free medium for at least 40 generations, a biomass obtained by multiplying the stable cell clone under serum- and protein-free culturing conditions, and a method of preparing recombinant proteins by means of the biomass. Furthermore, the invention relates to a method of recovering stable recombinant cell clones.