发明申请
- 专利标题: Cationic substituted benzofurans as antimicrobial agents
- 专利标题(中): 阳离子取代的苯并呋喃作为抗微生物剂
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申请号: US11005524申请日: 2004-12-06
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公开(公告)号: US20050197378A1公开(公告)日: 2005-09-08
- 发明人: Richard Tidwell , Karl Werbovetz , Scott Franzblau , Svetlana Bakunova , Stanislav Bakunov
- 申请人: Richard Tidwell , Karl Werbovetz , Scott Franzblau , Svetlana Bakunova , Stanislav Bakunov
- 主分类号: A61K
- IPC分类号: A61K20060101 ; A61K31/343 ; A61K31/4178 ; C07D307/87
摘要:
A method of treating a Mycobacterium tuberculosis infection in a subject in need thereof by administering to the subject an effective amount of a cationic substituted benzofuran compound. Methods of treating microbial infections, including infections from protozoan pathogens, such as Leishmania donovani, Trypanosoma brucei rhodesiense, a Trypanosoma cruzi, and Plasmodium falciparum, and fungal pathogens, such as Candida albicans, Aspergillus fumigatus, and Cryptococcus neoformans, in a subject in need thereof by administering to the subject an effective amount of a cationic substituted benzofuran compound. Methods of synthesizing novel cationic substituted benzofuran compounds and the novel compounds themselves.
公开/授权文献
- US07417158B2 Cationic substituted benzofurans as antimicrobial agents 公开/授权日:2008-08-26