发明申请
US20050202008A1 Promotion or inhibition of angiogenesis and cardiovascularization by tumor necrosis factor ligand/receptor homologs
审中-公开
通过肿瘤坏死因子配体/受体同系物促进或抑制血管生成和心血管化
- 专利标题： Promotion or inhibition of angiogenesis and cardiovascularization by tumor necrosis factor ligand/receptor homologs
- 专利标题（中）： 通过肿瘤坏死因子配体/受体同系物促进或抑制血管生成和心血管化
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申请号： US11032294申请日： 2005-01-10
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公开(公告)号： US20050202008A1公开(公告)日： 2005-09-15
- 发明人: P. Mickey Williams , Mary Gerritsen
- 申请人： P. Mickey Williams , Mary Gerritsen
- 申请人地址： US CA South San Francisco 94080
- 专利权人： Genentech, Inc.
- 当前专利权人： Genentech, Inc.
- 当前专利权人地址： US CA South San Francisco 94080
- 主分类号： G01N33/50
- IPC分类号： G01N33/50 ; A61K38/00 ; A61K38/17 ; A61K39/395 ; A61K45/00 ; A61P1/04 ; A61P3/10 ; A61P7/02 ; A61P7/10 ; A61P9/00 ; A61P9/04 ; A61P9/10 ; A61P9/12 ; A61P9/14 ; A61P11/00 ; A61P13/12 ; A61P15/00 ; A61P17/02 ; A61P17/06 ; A61P19/10 ; A61P21/00 ; A61P25/00 ; A61P25/14 ; A61P25/16 ; A61P25/28 ; A61P27/02 ; A61P27/06 ; A61P29/00 ; A61P35/00 ; A61P41/00 ; A61P43/00 ; C07K14/47 ; C12N15/09 ; C12Q1/02 ; G01N33/15 ; G01N33/53 ; G01N33/566 ; G01N33/574
摘要：
Compositions and methods are disclosed for stimulating or inhibiting angiogenesis and/or cardiovascularization in mammals, including humans. Pharmaceutical compositions are based on polypeptides or antagonists thereto that have been identified for one or more of these uses. Disorders that can be diagnosed, prevented, or treated by the compositions herein include trauma such as wounds, various cancers, and disorders of the vessels including atherosclerosis and cardiac hypertrophy.
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