发明申请
- 专利标题: New compounds
- 专利标题(中): 新化合物
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申请号: US10997675申请日: 2004-11-24
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公开(公告)号: US20050239841A1公开(公告)日: 2005-10-27
- 发明人: Andrew Browning , Jonas Nilsson , Martin Scobie , Johan Angbrant , Rune Ringom
- 申请人: Andrew Browning , Jonas Nilsson , Martin Scobie , Johan Angbrant , Rune Ringom
- 优先权: SE0303182-0 20031126
- 主分类号: A61K31/405
- IPC分类号: A61K31/405 ; A61K31/416 ; A61K31/4178 ; A61K31/454 ; C07D209/12 ; C07D401/04 ; C07D401/06 ; C07D401/12 ; C07D403/06 ; C07D403/12 ; C07D405/04 ; C07D405/12 ; C07D409/12 ; C07D413/12 ; C07D417/12 ; C07D43/02
摘要:
The invention relates to compounds of the general formula (I) wherein R0, R1, R2, R3, R4, R5, R6, R7, R8, R9, Ar, and X are as defined in the description, or a pharmaceutically acceptable salt, hydrates, geometrical isomers, racemates, tautomers, optical isomers, N-oxides and prodrug forms thereof. The compounds may be used for the treatment or prophylaxis of disorders related to the MCH1R receptor and for modulation of appetite. The invention also relates to such use as well as to pharmaceutical formulations comprising a compound of formula (I).
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