公开(公告)号：US20140199693A1

公开(公告)日：2014-07-17

申请号：US14006089

申请日：2012-01-16

申请人： Thomas Wurdinger ,  Rolf Jonas Nilsson

发明人： Thomas Wurdinger ,  Rolf Jonas Nilsson

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6834 ,  C12Q1/6886 ,  C12Q2600/156 ,  C12Q2600/158

摘要： The present invention relates to a method of analysing a blood sample of a subject for the presence of a disease marker, said method comprising the steps of a) extracting nucleic acid from anucleated blood cells in said blood sample to provide an anucleated blood cells-extracted nucleic acid fraction, and b) analysing said anucleated blood cells-extracted nucleic acid fraction for the presence of a disease marker, wherein said disease marker is a disease-specific mutation in a gene of a cell of said subject, or wherein said disease marker is a disease-specific expression profile of genes of a cell of said subject.

摘要翻译： 本发明涉及一种分析患者血液样本中疾病标志物存在的方法，所述方法包括以下步骤：a）从所述血液样品中的未核化血细胞提取核酸，以提供无核细胞提取的 核酸级分，以及b）分析所述无核细胞提取的核酸级分是否存在疾病标志物，其中所述疾病标志物是所述受试者的细胞基因中的疾病特异性突变，或其中所述疾病标记 是所述受试者的细胞的基因的疾病特异性表达谱。

公开(公告)号：US20100258079A1

公开(公告)日：2010-10-14

申请号：US12739157

申请日：2008-10-22

申请人： Erik Ott ,  Jonas Nilsson

发明人： Erik Ott ,  Jonas Nilsson

IPC分类号： F02D13/04 ,  G01M15/00

CPC分类号： F01L13/065 ,  F01L1/08 ,  F01L1/181 ,  F01L1/20 ,  F01L1/267 ,  F01L9/02 ,  F01L9/026 ,  F01L2105/00 ,  F01L2820/01 ,  F02D13/04 ,  F02D41/221 ,  Y02T10/40

摘要： In a method for reducing engine vibrations during engine braking with a malfunctioning engine brake, the engine brake includes an arrangement for altering a timing of at least one exhaust valve and an arrangement for varying an exhaust gas back pressure. The method includes detecting piston acceleration for each cylinder in the engine during the use of the engine brake, comparing the detected piston acceleration with a predetermined reference value, decreasing exhaust gas back pressure during engine braking if at least one piston is detected with a piston acceleration deviating more than a predefined amount from the predetermined reference value so that the piston acceleration will be falling within the predefined amount from the predetermined reference value.

摘要翻译： 在用发动机制动故障的发动机制动期间减少发动机振动的方法中，发动机制动器包括用于改变至少一个排气门的定时和用于改变排气背压的装置的装置。 该方法包括在发动机制动器的使用期间检测发动机中的每个气缸的活塞加速度，将检测到的活塞加速度与预定的参考值进行比较，如果在活塞加速度下检测到至少一个活塞，则在发动机制动期间减小排气背压 从预定的参考值偏移大于预定义的量，使得活塞加速度将从预定参考值落入预定义的量。

公开(公告)号：US20100191421A1

公开(公告)日：2010-07-29

申请号：US12670415

申请日：2007-08-15

申请人： Jonas Nilsson

发明人： Jonas Nilsson

IPC分类号： B62D6/00

CPC分类号： B62D15/025 ,  B60W10/20 ,  B60W50/14 ,  B60W2050/0026 ,  B60W2420/403 ,  B60W2420/52 ,  B60W2510/20 ,  B60W2520/14 ,  B60W2520/28 ,  B60W2550/402 ,  B62D6/003

摘要： A system and an operating method are provided for supporting lane keeping of a vehicle equipped with a steering device. The system and operating method include providing vehicle related information; providing environment related information; combining vehicle and environment related information; predicting a future trajectory of the vehicle based on vehicle and environment related information; estimating a desired lateral lane position of the vehicle and/or a guiding force; comparing the future trajectory and the desired lateral lane position; deciding if a guiding force is to be provided to the steering device; and, if guiding force is to be provided, defining an amount of said guiding force depending on a hierarchically ordered set describing a predetermined driving behavior of the vehicle, adapting the amount of guiding force depending on the direction in which the vehicle is intended to move and activating one or more actuators for supplying the adapted amount of guiding force to the steering device.

摘要翻译： 提供了一种用于支持配备有转向装置的车辆的车道保持的系统和操作方法。 系统和操作方法包括提供车辆相关信息; 提供环境相关信息; 结合车辆与环境相关信息; 基于车辆和环境相关信息预测车辆的未来轨迹; 估计车辆的期望侧车道位置和/或导向力; 比较未来轨迹和所需的横向车道位置; 决定是否向转向装置提供引导力; 并且如果要提供导向力，则根据描述车辆的预定驾驶行为的分级有序集来限定所述导向力的量，根据车辆将要移动的方向来适配导向力量 以及致动一个或多个致动器，以向转向装置提供适当量的引导力。

公开(公告)号：US06759401B2

公开(公告)日：2004-07-06

申请号：US10269670

申请日：2002-10-11

申请人： Björn Nilsson ,  Jan Tejbrant ,  Benjamin Pelcman ,  Erik Ringberg ,  Markus Thor ,  Jonas Nilsson ,  Mattias Jönsson

发明人： Björn Nilsson ,  Jan Tejbrant ,  Benjamin Pelcman ,  Erik Ringberg ,  Markus Thor ,  Jonas Nilsson ,  Mattias Jönsson

IPC分类号： A61K3133

摘要： The invention relates to compounds of the general formula (I): wherein Ar is optionally substituted aryl or heteroaryl; A is (i) —O—, —S—, —SO2—, —NH—, (ii) a C1-4-alkyl- or C1-6-acyl-substituted nitrogen atom or (iii) a C1-8-alkylene chain or a heteroalkylene chain having 2 to 8 chain atoms, which optionally contains at least one unsaturation, and which may be substituted and/or contain a bridge to form a saturated or partially or fully unsaturated ring having 3-8 ring members; B is —C(R4)(R5)—, —OC(R4)(R5)—, —N(R6)C(R4)(R5)—, —N(R6)—, —O—, —S— or —SO2—; R is optionally substituted C3-8-cycloalkyl, aryl or heteroaryl; R1 is (i) a saturated or unsaturated azacyclic or aminoazacyclic ring, or a saturated diazacyclic or aminodiazacyclic ring, which has 4 to 7 ring members, or a saturated aminoazabicyclic, azabicyclic or diazabicyclic ring which has 7 to 10 ring members, which rings optionally are substituted in one or more positions, or a group —[C(R4)(R5)]xN(R2a)(R3a)]; R2a, R3a, R4, R5, R6 and x are as defined in the claims, and n is 0 or 1; and pharmaceutically acceptable salts, hydrates and prodrug forms thereof The compounds may be prepared by per se conventional methods and can be used for treating a human or animal subject suffering from a serotonin-related disorder, such as eating disorders, especially obesity, memory disorders, schizophrenia, mood disorders, anxiety disorders, pain, sexual dysfunctions, and urinary disorders The invention also relates to such use as well as to pharmaceutical compositions comprising a compound of formula (I)

公开(公告)号：US6139315A

公开(公告)日：2000-10-31

申请号：US331209

申请日：1999-09-02

申请人： Goran Berglund ,  Jonas Nilsson

发明人： Goran Berglund ,  Jonas Nilsson

IPC分类号： C03B5/237 ,  F27D17/00 ,  F28D7/14

CPC分类号： F27D17/004 ,  C03B5/237 ,  Y02P40/535

摘要： A recuperator for furnaces includes a set of tubes, which are installed in a secondary chamber (1) which is located behind a main combustion chamber of the furnace and through which hot fumes can pass from the main combustion chamber towards an outlet. The task of the tubes is to recuperate thermal energy from the fumes by bringing a combustion gas to pass through the tubes on its way to burners in the main combustion chamber. The different tubes of the tube set are designed as individual units (8) each one of which is removably inserted in the secondary chamber (1) through holes in the walls (4) thereof. In the mounted condition each tube has a closed portion projecting into the secondary chamber as well as a portion projecting from the outside of the walls of the secondary chamber, the latter portion having inlets and outlets for cold and preheated combustion gas respectively.

摘要翻译： PCT No.PCT / SE97 / 02150 Sec。 371 1999年9月2日第 102（e）1999年9月2日PCT 1997年12月18日PCT公布。 第WO98 / 27017号公报 日期1998年6月25日用于炉的换热器包括一组管，其安装在位于炉的主燃烧室后面的次级室（1）中，并且热烟雾可以通过该主燃烧室从主燃烧室朝向 出口。 管的任务是通过使燃烧气体在通向主燃烧室中的燃烧器的途中通过管而从烟气中恢复热能。 管组的不同管被设计为单独的单元（8），每个单元通过其壁（4）中的孔可移除地插入次室（1）中。 在安装状态下，每个管具有突出到次级室中的封闭部分以及从第二室的壁的外部突出的部分，后者部分分别具有用于冷和预热的燃烧气体的入口和出口。

公开(公告)号：US09238515B2

公开(公告)日：2016-01-19

申请号：US13515998

申请日：2010-12-15

申请人： Jens Persson ,  Göran Hermodsson ,  Jonas Nilsson ,  Simo Vallenback

发明人： Jens Persson ,  Göran Hermodsson ,  Jonas Nilsson ,  Simo Vallenback

IPC分类号： B65B1/04 ,  B65B3/02 ,  B65B31/02 ,  B65B5/02 ,  B65B9/20 ,  B65B31/04

CPC分类号： B65B9/20 ,  B65B31/045

摘要： A filling assembly for filling of a tube of packaging material having a seal starting at a first level, comprises a conduit arranged to lead liquid into the tube of packaging material below said first level and a passage arranged to eject gas through openings into the tube of packaging material below said first level. The filling assembly is characterized in that a gasket is arranged to provide a seal between said filling assembly and said tube of packaging material upstream said openings such that the overpressure P1 downstream the gasket may exceed an ambient pressure Pa upstream the gasket.

摘要翻译： 一种用于填充具有从第一层开始的密封剂的包装材料管的填充组件，包括布置成将液体引导到所述第一水平面以下的包装材料管中的导管，以及设置成将气体通过开口喷射到管 包装材料低于第一级。 填充组件的特征在于，垫圈布置成在所述填充组件和所述开口之上的所述包装材料管之间提供密封，使得垫圈下游的超压P1可以超过垫圈上游的环境压力Pa。

公开(公告)号：US20150103759A1

公开(公告)日：2015-04-16

申请号：US14363148

申请日：2011-12-09

申请人： Anders Holm ,  Håkan Axelsson ,  Anders Hallberg ,  Oskar Myrberg ,  Jonas Nilsson

发明人： Anders Holm ,  Håkan Axelsson ,  Anders Hallberg ,  Oskar Myrberg ,  Jonas Nilsson

IPC分类号： H04W72/12 ,  H04L5/00

CPC分类号： H04W72/1278 ,  H04L5/003 ,  H04W76/11

摘要： A method, in a base station subsystem (10), of allocating radio resources to mobile stations (20) in a wireless communication system (1) involves the base station subsystem (10) assigning a respective Temporary Block Flow (TBF) to each mobile station (20) in a cell (40) in the communication system (1), and then assigning to each TBF a Temporary Flow Identity (TFI), at least one Packet Data Channel (PDCH), and an Uplink State Flag (USF) if the TBF is an uplink TBF. The base station subsystem (10) then selects different training sequences from a plurality of available training sequences and assigns a respective different selected training sequence to two or more TBFs wherein these two or more TBFs share the same assigned Temporary Flow Identity (TFI), the same assigned Packet Data Channel (PDCH), and/or the same assigned Uplink State Flag (USF) if the TBF is an uplink TBF.

摘要翻译： 一种在基站子系统（10）中向无线通信系统（1）中的移动台（20）分配无线电资源的方法，其特征在于，所述基站子系统（10）将相应的临时块流（TBF）分配给每个移动台 在通信系统（1）中的小区（40）中的站（20），然后向每个TBF分配临时流标识（TFI），至少一个分组数据信道（PDCH）和上行链路状态标志（USF） 如果TBF是上行链路TBF。 然后，基站子系统（10）从多个可用的训练序列中选择不同的训练序列，并将相应不同的选择的训练序列分配给两个或更多个TBF，其中这两个或更多TBF共享相同的分配临时流标识（TFI）， 相同的分配数据信道（PDCH），和/或相同的分配的上行链路状态标志（USF），如果TBF是上行链路TBF。

公开(公告)号：US08916387B2

公开(公告)日：2014-12-23

申请号：US13881387

申请日：2011-10-28

申请人： Jonas Nilsson ,  Adnan Halim ,  Göran Larson ,  Kaj Blennow ,  Gunnar Brinkmalm ,  Erik Portelius ,  Henrik Zetterberg

发明人： Jonas Nilsson ,  Adnan Halim ,  Göran Larson ,  Kaj Blennow ,  Gunnar Brinkmalm ,  Erik Portelius ,  Henrik Zetterberg

IPC分类号： G01N24/00 ,  G01N24/14 ,  G01N33/68 ,  H01J49/00 ,  A61K39/00

CPC分类号： G01N33/6896 ,  A61K39/0007 ,  C07K16/18 ,  G01N2333/4709 ,  G01N2440/38 ,  G01N2800/2821 ,  G01N2800/50 ,  G01N2800/52 ,  H01J49/0027 ,  Y10T436/24

摘要： Methods are provided for the prevention, treatment and diagnosis of Alzheimer's disease, based on the glycosylation pattern of amyloid-beta peptides in body fluids and tissues.

摘要翻译： 基于体液和组织中淀粉样蛋白-β肽的糖基化模式，提供了用于预防，治疗和诊断阿尔茨海默病的方法。

公开(公告)号：US20140256590A1

公开(公告)日：2014-09-11

申请号：US14237424

申请日：2012-08-08

申请人： Thomas Würdinger ,  Rolf Jonas Nilsson

发明人： Thomas Würdinger ,  Rolf Jonas Nilsson

IPC分类号： C12Q1/68 ,  G01N33/50

CPC分类号： C12Q1/6883 ,  C12Q1/6879 ,  C12Q2600/156 ,  C12Q2600/158 ,  G01N33/5023 ,  G01N33/689 ,  G01N33/86 ,  G01N2800/368 ,  G01N2800/385

摘要： The present invention relates to a method of analysing a blood sample of a subject carrying a foetus for the presence of a foetal disease or condition marker, said method comprising the steps of a) extracting nucleic acid from anucleated blood cells, preferably thrombocytes, in said blood sample to provide an anucleated blood cell-extracted nucleic acid fraction, and b) analysing said anucleated blood cell-extracted nucleic acid fraction for the presence of a foetal disease or condition marker, wherein said foetal disease or condition marker is a nucleic acid of a foetus, or wherein said foetal disease or condition marker is a foetal disease or condition-specific expression profile of genes of a cell of said foetus.

摘要翻译： 本发明涉及一种分析胎儿疾病或病症标记物携带胎儿的血液样本的方法，所述方法包括以下步骤：a）从所述胎儿疾病或病症标记中的未成熟血细胞，优选血小板提取核酸， 提供无核细胞提取的核酸级分的血液样品，以及b）分析所述无核细胞提取的核酸部分是否存在胎儿疾病或病症标记物，其中所述胎儿疾病或病症标记是 胎儿，或其中所述胎儿疾病或病症标记是所述胎儿的细胞的基因的胎儿疾病或条件特异性表达谱。

公开(公告)号：US20140037658A1

公开(公告)日：2014-02-06

申请号：US13881387

申请日：2011-10-28

申请人： Jonas Nilsson ,  Adnan Halim ,  Göran Larson ,  Kaj Blennow ,  Gunnar Brinkmalm ,  Erik Portelius ,  Henrik Zetterberg

发明人： Jonas Nilsson ,  Adnan Halim ,  Göran Larson ,  Kaj Blennow ,  Gunnar Brinkmalm ,  Erik Portelius ,  Henrik Zetterberg

IPC分类号： G01N33/68 ,  H01J49/00 ,  A61K39/00

CPC分类号： G01N33/6896 ,  A61K39/0007 ,  C07K16/18 ,  G01N2333/4709 ,  G01N2440/38 ,  G01N2800/2821 ,  G01N2800/50 ,  G01N2800/52 ,  H01J49/0027 ,  Y10T436/24

摘要： Methods are provided for the prevention, treatment and diagnosis of Alzheimer's disease, based on the glycosylation pattern of amyloid-beta peptides in body fluids and tissues.

摘要翻译： 基于体液和组织中淀粉样蛋白-β肽的糖基化模式，提供了用于预防，治疗和诊断阿尔茨海默病的方法。