发明申请
- 专利标题： Process for producing a plasma protein-containing medicament
- 专利标题（中）： 用于制备含血浆蛋白的药物的方法
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申请号： US11151295申请日： 2005-06-14
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公开(公告)号： US20050249815A1公开(公告)日： 2005-11-10
- 发明人: Wolfgang Teschner , Yendra Linnau , Sonja Svatos , Herwig Igel
- 申请人： Wolfgang Teschner , Yendra Linnau , Sonja Svatos , Herwig Igel
- 申请人地址： AT Vienna
- 专利权人： Immuno Aktiengesellschaft
- 当前专利权人： Immuno Aktiengesellschaft
- 当前专利权人地址： AT Vienna
- 优先权： ATA1633/96 19960916
- 主分类号： A61K35/14
- IPC分类号： A61K35/14 ; A61K38/00 ; A61K38/17 ; C07K14/76 ; C07K16/06 ; A61K35/16
摘要：
There is disclosed a method of preparing a plasma-protein-containing medicament from citrated plasma or from a citrate-containing plasma fraction, the medicament being substantially free from undesired metals, which method comprises the following steps: exchanging the citrate and optionally citrate-bound metals in a plasma-protein-containing solution for a water-soluble mono- or dicarboxylate or for an organic mono- or dicarboxylic acid under non-precipitating conditions, recovering the plasma protein or the plasma proteins, and finishing the medicament.
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