发明申请
US20050255446A1 Perfusion system and apparatus for automated multi-channel patch-clamp recordings utilizing inside-out whole-cell configuration
失效
灌注系统和装置，用于利用内向外全细胞配置的自动化多通道膜片钳记录
- 专利标题： Perfusion system and apparatus for automated multi-channel patch-clamp recordings utilizing inside-out whole-cell configuration
- 专利标题（中）： 灌注系统和装置，用于利用内向外全细胞配置的自动化多通道膜片钳记录
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申请号： US10843322申请日： 2004-05-12
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公开(公告)号： US20050255446A1公开(公告)日： 2005-11-17
- 发明人: Dmytro Vasylyev , Thomas Merrill , Mark Bowlby , Anton Federkiewicz
- 申请人： Dmytro Vasylyev , Thomas Merrill , Mark Bowlby , Anton Federkiewicz
- 申请人地址： US NJ Madison
- 专利权人： Wyeth
- 当前专利权人： Wyeth
- 当前专利权人地址： US NJ Madison
- 主分类号： C12M1/34
- IPC分类号： C12M1/34 ; C12Q1/02 ; G01N33/50
摘要：
A system and method for high throughput patch clamp measurements to study the effect of various chemicals on ion transfer channels is provided. One or more patch clamp configurations is established, each comprising a cell sealed to a pipette. The pipettes are affixed to a pipette fixture. The pipette fixture and a plate comprising one or more wells are relatively moved so that each cell is inside a well. Electrical properties of the cells are measured.
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