Invention Application
US20050260211A1 Compounds for intracellular delivery of therapeutic moieties to nerve cells
有权
将治疗性部分细胞内递送给神经细胞的化合物
- Patent Title: Compounds for intracellular delivery of therapeutic moieties to nerve cells
- Patent Title (中): 将治疗性部分细胞内递送给神经细胞的化合物
-
Application No.: US10652723Application Date: 2003-08-28
-
Publication No.: US20050260211A1Publication Date: 2005-11-24
- Inventor: Robert Webb , Constance McKee
- Applicant: Robert Webb , Constance McKee
- Main IPC: A61K47/30
- IPC: A61K47/30 ; A61K47/42 ; A61K47/48 ; A61P5/00 ; A61P25/00 ; A61P25/04 ; A61P31/12 ; A61K48/00 ; A61K39/395
Abstract:
A compound for delivering a non-cytotoxic therapeutic moiety into nerve cells, the compound having the general formula: B-L-TM where: B is a binding agent capable of selectively binding to a nerve cell surface receptor and mediating absorption of the compound by the nerve cell; TM is a therapeutic moiety which has a non-cytotoxic therapeutic effect when absorbed by a nerve cell; and L is a linker coupling B to TM.
Public/Granted literature
- US07678378B2 Compounds for intracellular delivery of therapeutic moieties to nerve cells Public/Granted day:2010-03-16
Information query
