发明申请
US20050261341A1 Novel processes for the preparation of (R)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
审中-公开
制备(R)-α-(2,3-二甲氧基苯基)-1- [2-(4-氟苯基)乙基] -4-哌啶甲醇的新方法
- 专利标题: Novel processes for the preparation of (R)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
- 专利标题(中): 制备(R)-α-(2,3-二甲氧基苯基)-1- [2-(4-氟苯基)乙基] -4-哌啶甲醇的新方法
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申请号: US11114381申请日: 2005-04-26
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公开(公告)号: US20050261341A1公开(公告)日: 2005-11-24
- 发明人: Wolfgang Laux , Gerard Guillamot , Frederick Laskovics , Chi-Hsin King , James Hitt , Sandra Stolz-Dunn , Ian Tomlinson , Johannes Koek
- 申请人: Wolfgang Laux , Gerard Guillamot , Frederick Laskovics , Chi-Hsin King , James Hitt , Sandra Stolz-Dunn , Ian Tomlinson , Johannes Koek
- 申请人地址: US NJ Bridgewater DE Frankfurt am Main
- 专利权人: Aventis Pharmaceuticals Inc.,Aventis Pharma Deutschland GmbH
- 当前专利权人: Aventis Pharmaceuticals Inc.,Aventis Pharma Deutschland GmbH
- 当前专利权人地址: US NJ Bridgewater DE Frankfurt am Main
- 主分类号: A61K31/445
- IPC分类号: A61K31/445 ; C07D211/20 ; C07D211/22
摘要:
The present invention provides various processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol. These processes may be characterized by the following scheme:
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