发明申请
- 专利标题： Benzimidazole derivative
- 专利标题（中）： 苯并咪唑衍生物
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申请号： US11129508申请日： 2005-05-16
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公开(公告)号： US20050267148A1公开(公告)日： 2005-12-01
- 发明人: Naoki Tsuchiya , Tsuyoshi Mizuno , Hiroshi Saitou , Yoshiyuki Matsumoto , Susumu Takeuchi , Naoki Hase
- 申请人： Naoki Tsuchiya , Tsuyoshi Mizuno , Hiroshi Saitou , Yoshiyuki Matsumoto , Susumu Takeuchi , Naoki Hase
- 专利权人： TEIJIN LIMITED
- 当前专利权人： TEIJIN LIMITED
- 优先权： JP10-200250(PAT.) 19980715; JP2000-007533(PAT.) 20000117; JP2000-392303(PAT.) 20001225
- 主分类号： A61K31/4184
- IPC分类号： A61K31/4184 ; A61K31/4745 ; C07D401/06 ; C07D403/06 ; C07D405/06 ; C07D409/06 ; C07D413/06 ; C07D471/02
摘要：
The present invention is a thiobenzimidazole derivative represented by the following formula (1) or a medically acceptable salt thereof wherein said thiobenzimidazole derivative and a medically acceptable salt thereof have a potent activity of inhibiting human chymase. Thus, they are potential preventive and/or therapeutic agents clinically applicable to various diseases in which human chymase is involved.