发明申请
US20050267153A1 Use of N-substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds for treating hepatitis virus infections
审中-公开
使用N-取代-1,5-二脱氧-1,5-亚氨基-D-葡萄糖醇化合物治疗肝炎病毒感染
- 专利标题： Use of N-substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds for treating hepatitis virus infections
- 专利标题（中）： 使用N-取代-1,5-二脱氧-1,5-亚氨基-D-葡萄糖醇化合物治疗肝炎病毒感染
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申请号： US10910197申请日： 2004-08-03
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公开(公告)号： US20050267153A1公开(公告)日： 2005-12-01
- 发明人: Richard Mueller , Martin Bryant , Richard Partis , Gary Jacob , Timothy Block , Raymond Dwek
- 申请人： Richard Mueller , Martin Bryant , Richard Partis , Gary Jacob , Timothy Block , Raymond Dwek
- 主分类号： A61K31/445
- IPC分类号： A61K31/445 ; A61K31/7042 ; A61K31/7052 ; A61K31/7064 ; A61K31/7068 ; A61K45/06 ; A61P1/16 ; A61P31/20 ; C07D211/46 ; C07H19/10
摘要：
Provided are methods and compositions for treating hepatitis virus infections in mammals, especially humans. The methods comprise (1) administering N-substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds alone or in combination with nucleoside antiviral agents, nucleotide antiviral agents, mixtures thereof, or immunomodulating/immunostimulating agents, or (2) administering N-substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds alone or in combination with nucleoside antiviral agents, nucleotide antiviral agents, or mixtures thereof, and immunomodulating/immuno-stimulating agents.