发明申请
- 专利标题: Methods of analysis of degraded nucleic acid samples
- 专利标题(中): 降解核酸样品的分析方法
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申请号: US11121849申请日: 2005-05-03
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公开(公告)号: US20050272080A1公开(公告)日: 2005-12-08
- 发明人: John Palma , Eric Schell , Alan Williams
- 申请人: John Palma , Eric Schell , Alan Williams
- 申请人地址: US CA Santa Clara
- 专利权人: Affymetrix, INC.
- 当前专利权人: Affymetrix, INC.
- 当前专利权人地址: US CA Santa Clara
- 主分类号: C12M1/34
- IPC分类号: C12M1/34 ; C12Q1/68
摘要:
The invention provides arrays for analysis of compromised nucleic acid samples, for example, nucleic acids obtained from formalin fixed paraffin embedded samples and methods to analyzed these compromised samples. Arrays are disclosed in which the probe selection region used to select probes for the array is the 300 bases of the target MRNA that are immediately upstream of the start of the poly(A) tail of the mRNA. The probes selected for the array are more biased toward the 3′ end of the mRNA than other arrays that are currently available.
公开/授权文献
- US07374927B2 Methods of analysis of degraded nucleic acid samples 公开/授权日:2008-05-20
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