Invention Application
- Patent Title: Pyrimidine compound and medical use thereof
- Patent Title (中): 嘧啶化合物及其医疗用途
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Application No.: US11150792Application Date: 2005-06-10
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Publication No.: US20060014768A1Publication Date: 2006-01-19
- Inventor: Hisashi Kawasaki , Hiroyuki Abe , Kazuhide Hayakawa , Tetsuya Iida , Shinichi Kikuchi , Takayuki Yamaguchi , Toyomichi Nanayama , Hironori Kurachi , Masahiro Tamaru , Yoshikazu Hori , Mitsuru Takahashi , Takayuki Yoshida , Toshiyuki Sakai
- Applicant: Hisashi Kawasaki , Hiroyuki Abe , Kazuhide Hayakawa , Tetsuya Iida , Shinichi Kikuchi , Takayuki Yamaguchi , Toyomichi Nanayama , Hironori Kurachi , Masahiro Tamaru , Yoshikazu Hori , Mitsuru Takahashi , Takayuki Yoshida , Toshiyuki Sakai
- Applicant Address: JP Tokyo
- Assignee: Japan Tobacco Inc.
- Current Assignee: Japan Tobacco Inc.
- Current Assignee Address: JP Tokyo
- Priority: JP2004-174770 20040611; JP2004-327111 20041110
- Main IPC: A61K31/513
- IPC: A61K31/513 ; C07D405/02
Abstract:
The present invention relates to a pyrimidine compound or a pharmaceutically acceptable salt thereof represented by the following formula [I] wherein each symbol is as defined in the specification and a method of therapeutically or prophylactically treating an undesirable cell proliferation, comprising administering such a compound. The compound of the present invention has superior activity in suppressing undesirable cell proliferation, particularly, an antitumor activity, and is useful as an antitumor agent for the prophylaxis or treatment of cancer, rheumatism, and the like. In addition, the compound of the present invention can be a more effective antitumor agent when used in combination with other antitumor agents such as an alkylating agent or metabolism antagonist.
Public/Granted literature
- US07378423B2 Pyrimidine compound and medical use thereof Public/Granted day:2008-05-27
Information query
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