发明申请
US20060069106A1 Tetrahydroquinazolin-4(3H)-one-related and tetrahydropyrido[2,3-D]pyrimidin-4(3H)-one-related compounds, compositions and methods for their use
失效
四氢喹唑啉-4（3H） - 酮相关和四氢吡啶并[2,3-D]嘧啶-4（3H） - 酮相关化合物，其使用的组合物和方法
![Tetrahydroquinazolin-4(3H)-one-related and tetrahydropyrido[2,3-D]pyrimidin-4(3H)-one-related compounds, compositions and methods for their use](/docs/US/2006-03-30/US20060069106A1/abs.jpg.600x600.jpg)
- 专利标题： Tetrahydroquinazolin-4(3H)-one-related and tetrahydropyrido[2,3-D]pyrimidin-4(3H)-one-related compounds, compositions and methods for their use
- 专利标题（中）： 四氢喹唑啉-4（3H） - 酮相关和四氢吡啶并[2,3-D]嘧啶-4（3H） - 酮相关化合物，其使用的组合物和方法
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申请号： US11168006申请日： 2005-06-27
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公开(公告)号： US20060069106A1公开(公告)日： 2006-03-30
- 发明人: Zice Fu , Michael Johnson , An-Rong Li , Andrew Marcus , Julio Medina , Philippe Bergeron , Xiaoqi Chen , Xiaohui Du , Jeffrey Deignan , Jason Duquette , Darin Gustin , Jeffrey Mihalic
- 申请人： Zice Fu , Michael Johnson , An-Rong Li , Andrew Marcus , Julio Medina , Philippe Bergeron , Xiaoqi Chen , Xiaohui Du , Jeffrey Deignan , Jason Duquette , Darin Gustin , Jeffrey Mihalic
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; C07D487/02
![Tetrahydroquinazolin-4(3H)-one-related and tetrahydropyrido[2,3-D]pyrimidin-4(3H)-one-related compounds, compositions and methods for their use](/abs-image/US/2006/03/30/US20060069106A1/abs.jpg.150x150.jpg)
摘要：
Compounds are provided having the formula: wherein variables A1, A2, A3, A4, R1, R2, R3, R4, Q and L are as described herein. The subject compounds are useful for treatment of inflammatory and immune conditions and diseases. Compositions and methods of treatment using the subject compounds are also provided. For example, the subject methods are useful for treatment of inflammatory and immune disorders and disease such as multiple sclerosis, rheumatoid arthritis, psoriasis, and inflammatory bowel disease.
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