发明申请
US20060078899A1 Methods and compositions for reducing label variation in array-based comparative genome hybridization assays
审中-公开
基于阵列的比较基因组杂交测定中减少标记变异的方法和组合物
- 专利标题: Methods and compositions for reducing label variation in array-based comparative genome hybridization assays
- 专利标题(中): 基于阵列的比较基因组杂交测定中减少标记变异的方法和组合物
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申请号: US10964505申请日: 2004-10-12
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公开(公告)号: US20060078899A1公开(公告)日: 2006-04-13
- 发明人: Alicia Scheffer , Paige Anderson , Diane Ilsley , Michael Barrett , Bo Curry
- 申请人: Alicia Scheffer , Paige Anderson , Diane Ilsley , Michael Barrett , Bo Curry
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C12P19/34
摘要:
Methods and compositions for producing a labeled population of nucleic acids for use in an array-based comparative genome hybridization (CGH) assay are provided. In general, the methods involve cleaving a genomic source to produce a sample containing nucleic acid fragments, and end-labeling the nucleic acid fragments to provide a population of nucleic acids having a terminal label. Kits and systems for use in practicing the subject methods are also provided.
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