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发明申请
US20060106028A1 Polycyclic aromatics and derivatives thereof and processes for their preparation 审中-公开
多环芳烃及其衍生物及其制备方法

Polycyclic aromatics and derivatives thereof and processes for their preparation
摘要：
This invention relates to novel biologically active polycyclic aromatics produced by cultivation of Micromonospora echinospora ssp. challisensis NRRL 12255. The invention also relates to their pharmaceutically acceptable salts, prodrugs and derivatives, and to methods of obtaining them by post-biosynthesis chemical modification. The invention further relates to the use of the polycyclic aromatics and their derivatives in the preparation of medicaments for the treatment of neoplastic conditions and bacterial infections.
摘要（中）：

本发明涉及通过种植小单孢菌（Sponomonospora echinospora ssp）生产的新型生物活性多环芳烃。 本发明还涉及其药学上可接受的盐，前药和衍生物，以及通过后生物合成化学修饰获得它们的方法。 本发明还涉及多环芳烃及其衍生物在制备用于治疗肿瘤性病症和细菌感染的药物中的用途。

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