发明申请
US20060142312A1 C6-aryl and heteroaryl substituted pyrido[2,3-D] pyrimidin-7-ones
审中-公开
C6芳基和杂芳基取代的吡啶并[2,3-D]嘧啶-7-酮
![C6-aryl and heteroaryl substituted pyrido[2,3-D] pyrimidin-7-ones](/docs/US/2006-06-29/US20060142312A1/abs.jpg.600x600.jpg)
- 专利标题： C6-aryl and heteroaryl substituted pyrido[2,3-D] pyrimidin-7-ones
- 专利标题（中）： C6芳基和杂芳基取代的吡啶并[2,3-D]嘧啶-7-酮
-
申请号： US11021037申请日： 2004-12-23
-
公开(公告)号： US20060142312A1公开(公告)日： 2006-06-29
- 发明人: Cathlin Flamme , Douglas Johnson , Dennis McNamara , Debra Sherry , Peter Toogood , Scott VanderWel
- 申请人： Cathlin Flamme , Douglas Johnson , Dennis McNamara , Debra Sherry , Peter Toogood , Scott VanderWel
- 专利权人： PFIZER INC
- 当前专利权人： PFIZER INC
- 主分类号： A61K31/675
- IPC分类号： A61K31/675 ; A61K31/519
![C6-aryl and heteroaryl substituted pyrido[2,3-D] pyrimidin-7-ones](/abs-image/US/2006/06/29/US20060142312A1/abs.jpg.150x150.jpg)
摘要：
The present invention provides substituted 2-aminopyridines of formula I, wherein R1, A1, W, X, and Y are as defined in the specification, useful in treating cell proliferative disorders. The novel compounds of the present invention are potent inhibitors of cyclin-dependent kinases 4 (Cdk4).