发明申请
- 专利标题: Process for producing pad based for transdermal drug administration, pad base for transdermal drug administration and needle
- 专利标题(中): 用于经皮药物给药的垫片的制备方法,用于透皮给药的针基和针
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申请号: US10560085申请日: 2004-06-10
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公开(公告)号: US20060163215A1公开(公告)日: 2006-07-27
- 发明人: Shinya Maenosono , Yasushi Suzuki , Hiroshi Akitomo , Hidetoshi Hamamoto , Masaki Ishibashi
- 申请人: Shinya Maenosono , Yasushi Suzuki , Hiroshi Akitomo , Hidetoshi Hamamoto , Masaki Ishibashi
- 优先权: JP2003-165250 20030610
- 国际申请: PCT/JP04/08514 WO 20040610
- 主分类号: B23K15/00
- IPC分类号: B23K15/00
摘要:
According to a conventional MicroPatch method, a drug is administrated by stinging the skin with a solid-core needle, and broadening a gap between the needle and the skin by vibration with a vibrator. Consequently, the object of the present invention is to provide a pad base for endermism capable of administrating a drug in the skin without vibration, and to provide a production process capable of easily obtaining the pad base. One side end of the thin metal wire is immersed in a solution containing a synthetic resin raw material in a lengthwise direction, the synthetic resin raw material solution adheres to a periphery of the thin metal wire, the synthetic resin raw material solution is hardened and then the thin metal wire is pulled out. There is obtained the minute needle 1 which is installed upright on the skin side of a patch base 2, wherein the minute needle is a hollow tubular body and the outer wall thereof is thickened toward the bottom. A drug in the hollow portion 3 of the minute needle 1 is injected in the skin and can be provided for endermism. Further, since the minute needle 1 spreads and is thickened toward the bottom, it hardly fractures.
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