发明申请
US20060163215A1 Process for producing pad based for transdermal drug administration, pad base for transdermal drug administration and needle 失效
用于经皮药物给药的垫片的制备方法,用于透皮给药的针基和针

Process for producing pad based for transdermal drug administration, pad base for transdermal drug administration and needle
摘要:
According to a conventional MicroPatch method, a drug is administrated by stinging the skin with a solid-core needle, and broadening a gap between the needle and the skin by vibration with a vibrator. Consequently, the object of the present invention is to provide a pad base for endermism capable of administrating a drug in the skin without vibration, and to provide a production process capable of easily obtaining the pad base. One side end of the thin metal wire is immersed in a solution containing a synthetic resin raw material in a lengthwise direction, the synthetic resin raw material solution adheres to a periphery of the thin metal wire, the synthetic resin raw material solution is hardened and then the thin metal wire is pulled out. There is obtained the minute needle 1 which is installed upright on the skin side of a patch base 2, wherein the minute needle is a hollow tubular body and the outer wall thereof is thickened toward the bottom. A drug in the hollow portion 3 of the minute needle 1 is injected in the skin and can be provided for endermism. Further, since the minute needle 1 spreads and is thickened toward the bottom, it hardly fractures.
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