发明申请
US20060165726A1 Remedies with the use of hollow protein nanoparticles presenting growth factor or the like
审中-公开
使用具有生长因子等的中空蛋白质纳米粒子的补救措施
- 专利标题： Remedies with the use of hollow protein nanoparticles presenting growth factor or the like
- 专利标题（中）： 使用具有生长因子等的中空蛋白质纳米粒子的补救措施
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申请号： US10509248申请日： 2003-03-05
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公开(公告)号： US20060165726A1公开(公告)日： 2006-07-27
- 发明人: Shunichi Kuroda , Katsuyuki Tanizawa , Akihiko Kondo , Masakazu Ueda , Masaharu Seno , Hidehiko Iwabuki
- 申请人： Shunichi Kuroda , Katsuyuki Tanizawa , Akihiko Kondo , Masakazu Ueda , Masaharu Seno , Hidehiko Iwabuki
- 申请人地址： JP Kawaguchi-shi, Saitama 332-0012
- 专利权人： JAPAN SCIENCE AND TECHNOLOGY AGENCY
- 当前专利权人： JAPAN SCIENCE AND TECHNOLOGY AGENCY
- 当前专利权人地址： JP Kawaguchi-shi, Saitama 332-0012
- 优先权： JP2002-97395 20020329
- 国际申请： PCT/JP03/02601 WO 20030305
- 主分类号： A61K39/29
- IPC分类号： A61K39/29 ; A61K39/245 ; A61K9/14
摘要：
The invention provides a disease-treating drug, specifically acting particular cells or tissues, which is based on protein hollow nanoparticles. The drug's therapeutic effects are confirmed through animal experiments. The invention also provides a treatment method using the drug. The disease-treating drug comprises a substance to be transferred into a cell for treatment of a disease (for example, cancer-treating, thymidine kinase gene of herpes simplex virus type 1) encapsulated in hollow nanoparticles containing particle-forming protein (for example, hepatitis B virus surface antigen protein modified to lose infectivity to inherent hepatocyte and also display a growth factor) displaying, for example, a growth factor.
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