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33 条记录 (耗时 0.018 秒)

    Novel Method For Producing Ethanol
    1.
    发明申请
    Novel Method For Producing Ethanol 审中-公开
    用于生产乙醇的新方法

    公开(公告)号：US20140120598A1

    公开(公告)日：2014-05-01

    申请号：US14128633

    申请日：2012-06-25

    申请人： Akihiko Kondo ,  Tomohisa Hasunuma

    发明人： Akihiko Kondo ,  Tomohisa Hasunuma

    IPC分类号： C12P7/10

    CPC分类号： C12P7/10 ,  C12N9/16 ,  Y02E50/16

    摘要： Provided is a novel method of producing ethanol by using a cellulose-based biomass as a raw material. In particular, provided is a novel method of producing ethanol by which ethanol can be effectively produced in the presence of a substance having an inhibitory action on fermentation of ethanol. Ethanol can be effectively produced by using a microorganism engineered to suppress the expression of at least one kind of phosphatase among the phosphatases intrinsically possessed by the microorganism, even under a condition where a substance that has heretofore been believed to have a fermentation inhibitory action, specifically, a weakly acidic substance and/or a furan compound are/is incorporated.

    摘要翻译： 提供了以纤维素类生物质为原料生产乙醇的新方法。 特别地，提供了一种生产乙醇的新方法，通过乙醇可以在对乙醇发酵具有抑制作用的物质的存在下有效地产生乙醇。 通过使用微生物工程改造来抑制微生物固有的磷酸酶中至少一种磷酸酶表达的微生物，即使在迄今为止被认为具有发酵抑制作用的物质的条件下也可有效地制备乙醇 ，掺入弱酸性物质和/或呋喃化合物。

    Production and use of yeast having increased cellulose hydrolysis ability
    2.
    发明授权
    Production and use of yeast having increased cellulose hydrolysis ability 有权
    生产和使用具有增加的纤维素水解能力的酵母

    公开(公告)号：US08574911B2

    公开(公告)日：2013-11-05

    申请号：US13063225

    申请日：2009-09-16

    申请人： Hideo Noda ,  Shohei Kaneko ,  Akihiko Kondo

    发明人： Hideo Noda ,  Shohei Kaneko ,  Akihiko Kondo

    IPC分类号： C12N15/74

    CPC分类号： C12P7/10 ,  C12N9/2437 ,  C12Y302/01004 ,  C12Y302/01021 ,  C12Y302/01091 ,  Y02E50/16

    摘要： The present invention provides a method for producing an yeast having an increased cellulose hydrolysis ability. The method includes the step of introducing increased integration copy numbers of both a gene for an enzyme capable of hydrolyzing crystalline cellulose and a gene for an enzyme capable of hydrolyzing noncrystalline cellulose into a noncellulolytic yeast to give a transformed yeast. The yeast having an increased cellulose hydrolysis ability can be suitably used for ethanol production from cellulose-based materials.

    摘要翻译： 本发明提供了具有增加的纤维素水解能力的酵母的制造方法。 该方法包括将能够水解结晶纤维素的酶的基因和能够将非结晶纤维素水解的酶的基因的基因的增加的整合拷贝数引入非溶解酵母以产生转化的酵母的步骤。 具有增加的纤维素水解能力的酵母可以适用于从纤维素基材料制备乙醇。

    Radiation Therapy Agent
    3.
    发明申请
    Radiation Therapy Agent 有权
    放射治疗剂

    公开(公告)号：US20130017266A1

    公开(公告)日：2013-01-17

    申请号：US13578836

    申请日：2011-02-17

    申请人： Chiaki Ogino ,  Tsutomu Tanaka ,  Ryohei Sasaki ,  Akihiko Kondo

    发明人： Chiaki Ogino ,  Tsutomu Tanaka ,  Ryohei Sasaki ,  Akihiko Kondo

    IPC分类号： A61K9/14 ,  A61P35/00 ,  C07K16/18 ,  C07K16/00 ,  A61K39/395 ,  B82Y5/00

    CPC分类号： A61K9/0019 ,  A61K33/40 ,  A61K41/0057 ,  A61K47/6835 ,  A61K2039/505 ,  A61N5/10 ,  A61N2005/1098 ,  C07K16/2863 ,  Y10T428/2982

    摘要： Provided is a radiotherapeutic agent, including a composite particle, which is obtained by binding a molecule that specifically recognizes a target to a substrate particle including titanium peroxide, and which generates reactive oxygen through irradiation with a radiation. Further, because the radiotherapeutic agent contains the molecule that specifically recognizes a target, the radiotherapeutic agent has a function of accumulating in the target. The radiotherapeutic agent is capable of enhancing effects of radiotherapy, and is capable of reducing side effects on a living body to efficiently attack the target.

    摘要翻译： 本发明提供一种放射治疗剂，包括复合颗粒，其通过将特异性识别靶标的分子与包含过氧化钛的底物颗粒结合而获得，并且通过辐射照射产生活性氧。 此外，由于放射治疗剂含有特异性识别靶标的分子，所以放射治疗剂具有累积在靶内的功能。 放射治疗剂能够增强放射疗法的作用，并且能够减少对活体的副作用以有效地攻击靶。

    Microorganism that displays biotin on cell surface
    4.
    发明授权
    Microorganism that displays biotin on cell surface 有权
    在细胞表面显示生物素的微生物

    公开(公告)号：US08252577B2

    公开(公告)日：2012-08-28

    申请号：US12431102

    申请日：2009-04-28

    申请人： Akihiko Kondo ,  Hideki Fukuda ,  Tsutomu Tanaka ,  Hideo Noda

    发明人： Akihiko Kondo ,  Hideki Fukuda ,  Tsutomu Tanaka ,  Hideo Noda

    IPC分类号： C12N1/20 ,  C12N1/00 ,  C12N9/10 ,  C12Q1/00 ,  C12Q1/48 ,  G01N33/567 ,  G01N33/53 ,  C12P21/06 ,  C12P21/04

    CPC分类号： C12N15/1037 ,  C12N9/93

    摘要： Provided is a microorganism that can display, on the cell surface, any molecules other than a molecule comprising amino acids, more specifically, a microorganism that displays biotin on a cell surface. The microorganism is capable of co-expressing a biotinylating enzyme and an acceptor peptide having a sequence recognized by the biotinylating enzyme, wherein the acceptor peptide is expressed on the cell surface, so that lysine of the acceptor peptide is biotinylated to display biotin on the cell surface. Also provided is a method for displaying an intended molecule, including not only a molecule comprising amino acids but also any molecules, on a cell surface of a microorganism.

    摘要翻译： 本发明提供能够在细胞表面上显示除氨基酸分子以外的任何分子，更具体地，在细胞表面上显示生物素的微生物的微生物。 微生物能够共表达生物素化酶和具有生物素化酶识别的序列的受体肽，其中受体肽在细胞表面上表达，使得受体肽的赖氨酸被生物素化以在细胞上显示生物素 表面。 还提供了在微生物的细胞表面上显示预期分子的方法，不仅包括包含氨基酸的分子，而且包括任何分子。

    Homolactic Fermentation from Pentose
    5.
    发明申请
    Homolactic Fermentation from Pentose 有权
    同醇发酵从Pentose

    公开(公告)号：US20120058528A1

    公开(公告)日：2012-03-08

    申请号：US13202218

    申请日：2010-02-15

    申请人： Akihiko Kondo ,  Kenji Okano ,  Hideo Noda

    发明人： Akihiko Kondo ,  Kenji Okano ,  Hideo Noda

    IPC分类号： C12P7/56 ,  C12N1/20

    CPC分类号： C12P7/56 ,  C12N9/88

    摘要： Provided is a lactic acid bacterium capable of homolactic fermentation using a pentose as a substrate, the lactic acid bacterium utilizing a pentose, and in which a phosphoketolase pathway is blocked and a pentose phosphate pathway is activated. Also provided is a method for producing lactic acid from a pentose using the lactic acid bacterium and a method for preparing the lactic acid bacterium.

    摘要翻译： 本发明提供能够使用戊糖作为基质进行均相发酵的乳酸菌，利用戊糖的乳酸菌，磷酸酮糖苷酶途径被阻断，磷酸戊糖途径被活化。 还提供了使用乳酸菌从戊糖生产乳酸的方法和制备乳酸菌的方法。

    METHOD FOR PRODUCING ETHANOL
    8.
    发明申请
    METHOD FOR PRODUCING ETHANOL 审中-公开
    生产乙醇的方法

    公开(公告)号：US20120282666A1

    公开(公告)日：2012-11-08

    申请号：US13512895

    申请日：2010-06-30

    申请人： Hideo Noda ,  Shohei Kaneko ,  Akihiko Kondo

    发明人： Hideo Noda ,  Shohei Kaneko ,  Akihiko Kondo

    IPC分类号： C12P7/10 ,  C08B1/00

    CPC分类号： C12P19/14 ,  C12P7/10 ,  C12P19/02 ,  Y02E50/16

    摘要： The present invention provides a method for producing ethanol, including: subjecting a cellulose-based material to a hot-water treatment and an ammonia treatment to obtain a fermentation substrate; and reacting the fermentation substrate with a yeast to produce ethanol. The present invention also provides a method for producing a fermentation substrate for ethanol production by a yeast, including: subjecting a cellulose material to a hot-water treatment and an ammonia treatment to obtain a fermentation substrate. Thus obtained fermentation substrate can enhance the ethanol production by yeast.

    摘要翻译： 本发明提供一种生产乙醇的方法，包括：对纤维素基材料进行热水处理和氨处理以获得发酵基材; 并使发酵底物与酵母反应以产生乙醇。 本发明还提供一种由酵母生产乙醇生产发酵底物的方法，包括：对纤维素材料进行热水处理和氨处理以获得发酵基质。 这样得到的发酵底物可以提高酵母的乙醇产量。