- 专利标题： Triazole compounds that modulate Hsp90 activity
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申请号： US11282119申请日： 2005-11-17
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公开(公告)号： US20060167070A1公开(公告)日： 2006-07-27
- 发明人: Weiwen Ying , David James , Shijie Zhang , Teresa Przewloka , Junghyun Chae , Dinesh Chimmanamada , Chi-Wan Lee , Elena Kostik , Howard Ng , Kevin Foley , Zhenjian Du , James Barsoum
- 申请人： Weiwen Ying , David James , Shijie Zhang , Teresa Przewloka , Junghyun Chae , Dinesh Chimmanamada , Chi-Wan Lee , Elena Kostik , Howard Ng , Kevin Foley , Zhenjian Du , James Barsoum
- 主分类号： A61K31/4196
- IPC分类号： A61K31/4196 ; C07D403/02 ; C07D249/12 ; C07D249/08
摘要：
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
公开/授权文献
- US07825148B2 Triazole compounds that modulate Hsp90 activity 公开/授权日：2010-11-02
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