发明申请
- 专利标题： Capsaicin receptor agonists
- 专利标题（中）： 辣椒素受体激动剂
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申请号： US11412526申请日： 2006-04-26
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公开(公告)号： US20060194805A1公开(公告)日： 2006-08-31
- 发明人: Rajagopal Bakthavatchalam , Charles Blum , Harry Brielmann , Timothy Caldwell , Daniel Cortright , Kevin Hodgetts , John Peterson , Xiaozhang Zheng
- 申请人： Rajagopal Bakthavatchalam , Charles Blum , Harry Brielmann , Timothy Caldwell , Daniel Cortright , Kevin Hodgetts , John Peterson , Xiaozhang Zheng
- 申请人地址： US CT Branford
- 专利权人： Neurogen Corporation
- 当前专利权人： Neurogen Corporation
- 当前专利权人地址： US CT Branford
- 主分类号： A61K31/525
- IPC分类号： A61K31/525 ; A61K31/517 ; A61K31/519 ; A61K31/498 ; C07D475/10 ; C07D487/02
摘要：
Capsaicin receptor agonists are provided. Such compounds are ligands that may be used to modulate VR1 activity in vivo or in vitro, and are particularly useful in the treatment of conditions responsive to capsaicin receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.
公开/授权文献
- US1625064A Combination tool 公开/授权日：1927-04-19
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