- 专利标题: Stabilization of hypoxia inducible factor (HIF) alpha
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申请号: US11495036申请日: 2006-07-28
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公开(公告)号: US20060258660A1公开(公告)日: 2006-11-16
- 发明人: Volkmar Guenzler-Pukall , Thomas Neff , Qingjian Wang , Michael Arend , Lee Flippin , Alex Melekhov
- 申请人: Volkmar Guenzler-Pukall , Thomas Neff , Qingjian Wang , Michael Arend , Lee Flippin , Alex Melekhov
- 申请人地址: US CA South San Francisco
- 专利权人: FibroGen, Inc.
- 当前专利权人: FibroGen, Inc.
- 当前专利权人地址: US CA South San Francisco
- 主分类号: A61K31/502
- IPC分类号: A61K31/502
摘要:
The present invention relates to methods of stabilizing the alpha subunit of hypoxia inducible factor (HIF). The invention further relates to methods of preventing, pretreating, or treating conditions associated with HIF, including ischemic and hypoxic conditions. Compounds for use in these methods are also provided.
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