发明申请
- 专利标题： Identification of anti-hiv compounds inhibiting virus assembly and binding of nucleocapsid protein to nucleic acid
- 专利标题（中）： 鉴定抗-Hiv化合物抑制病毒装配和核衣壳蛋白与核酸的结合
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申请号： US10528747申请日： 2003-10-08
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公开(公告)号： US20060263772A1公开(公告)日： 2006-11-23
- 发明人: Robert Shoemaker , Michael Currens , Alan Rein , Ya-Xiong Feng , Robert Fisher , Andrew Stephen , Karen Worthy , Shizuko Sei , Bruce Crise , Louis Henderson
- 申请人： Robert Shoemaker , Michael Currens , Alan Rein , Ya-Xiong Feng , Robert Fisher , Andrew Stephen , Karen Worthy , Shizuko Sei , Bruce Crise , Louis Henderson
- 申请人地址： US MD Rockville 20852
- 专利权人： The Government of the USA as Represented by the Secretary of the Dept. of Health and Human Service
- 当前专利权人： The Government of the USA as Represented by the Secretary of the Dept. of Health and Human Service
- 当前专利权人地址： US MD Rockville 20852
- 国际申请： PCT/US03/32086 WO 20031008
- 主分类号： C12Q1/70
- IPC分类号： C12Q1/70 ; C12Q1/68
摘要：
The invention provides methods and pharmaceutical compositions for inhibiting viral replication, particularly retroviral replication. The methods comprise administration of stibonic acid or diphenyl compounds that disrupt viral nucleocapsid binding to nucleic acids.
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