专利检索 ap:"Louis Henderson" 第 1 页

1.

发明申请
Identification of anti-hiv compounds inhibiting virus assembly and binding of nucleocapsid protein to nucleic acid 失效
标题翻译：鉴定抗-Hiv化合物抑制病毒装配和核衣壳蛋白与核酸的结合

公开(公告)号：US20060263772A1

公开(公告)日：2006-11-23

申请号：US10528747

申请日：2003-10-08

申请人： Robert Shoemaker , Michael Currens , Alan Rein , Ya-Xiong Feng , Robert Fisher , Andrew Stephen , Karen Worthy , Shizuko Sei , Bruce Crise , Louis Henderson

发明人： Robert Shoemaker , Michael Currens , Alan Rein , Ya-Xiong Feng , Robert Fisher , Andrew Stephen , Karen Worthy , Shizuko Sei , Bruce Crise , Louis Henderson

IPC分类号： C12Q1/70 , C12Q1/68

CPC分类号： A61K31/194 , A61K31/29 , A61K45/06 , G01N33/68

摘要： The invention provides methods and pharmaceutical compositions for inhibiting viral replication, particularly retroviral replication. The methods comprise administration of stibonic acid or diphenyl compounds that disrupt viral nucleocapsid binding to nucleic acids.

摘要翻译： 本发明提供用于抑制病毒复制，特别是逆转录病毒复制的方法和药物组合物。所述方法包括施用破坏病毒核衣壳与核酸结合的苯乙烯酸或二苯基化合物。