- 专利标题: Delivery of antihistamines through an inhalation route
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申请号: US11507986申请日: 2006-08-22
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公开(公告)号: US20060286043A1公开(公告)日: 2006-12-21
- 发明人: Joshua Rabinowitz , Alejandro Zaffaroni
- 申请人: Joshua Rabinowitz , Alejandro Zaffaroni
- 申请人地址: US CA Palo Alto
- 专利权人: Alexza Pharmaceuticals, Inc.
- 当前专利权人: Alexza Pharmaceuticals, Inc.
- 当前专利权人地址: US CA Palo Alto
- 主分类号: A61K31/55
- IPC分类号: A61K31/55 ; A61K31/5415 ; A61K31/495 ; A61K31/473 ; A61K9/14 ; A61L9/04
摘要:
The present invention relates to the delivery of antihistamines through an inhalation route. Specifically, it relates to aerosols containing antihistamines that are used in inhalation therapy. In a method aspect of the present invention, an antihistamine is delivered to a patient through an inhalation route. The method comprises: a) heating a composition, wherein the composition comprises an antihistamine, to form a vapor; and, b) allowing the vapor to cool, thereby forming a condensation aerosol comprising particles with less than 5% antihistamine drug degradation products. In a kit aspect of the present invention, a kit for delivering an antihistamine through an inhalation route is provided which comprises: a) a thin coating of an antihistamine drug composition and b) a device for dispensing said thin coating as a condensation aerosol.
公开/授权文献
- US07491047B2 Delivery of antihistamines through an inhalation route 公开/授权日:2009-02-17
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