发明申请
- 专利标题： Azaindazole compounds and methods of use
- 专利标题（中）： 阿扎唑类化合物及其使用方法
-
申请号： US11474132申请日： 2006-06-22
-
公开(公告)号： US20070010524A1公开(公告)日： 2007-01-11
- 发明人: Penglie Zhang , Andrew Pennell , John J. Wright , Wei Chen , Manmohan Leleti , Yandong Li , Lianfa Li , Yuan Xu
- 申请人： Penglie Zhang , Andrew Pennell , John J. Wright , Wei Chen , Manmohan Leleti , Yandong Li , Lianfa Li , Yuan Xu
- 申请人地址： US CA Mountain View
- 专利权人： ChemoCentryx, Inc.
- 当前专利权人： ChemoCentryx, Inc.
- 当前专利权人地址： US CA Mountain View
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; A61K31/519 ; C07D487/02 ; C07D403/02
摘要：
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.
公开/授权文献
- US07524845B2 Azaindazole compounds and methods of use 公开/授权日：2009-04-28
信息查询
IPC分类:
