- 专利标题: CYTOKINE ZALPHA11 LIGAND ANTIBODIES
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申请号: US11549868申请日: 2006-10-16
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公开(公告)号: US20070041974A1公开(公告)日: 2007-02-22
- 发明人: Julia Novak , Scott Presnell , Cindy Sprecher , Donald Foster , Richard Holly , Jane Gross , Janet Johnston , Andrew Nelson , Stacey Dillon , Angela Hammond
- 申请人: Julia Novak , Scott Presnell , Cindy Sprecher , Donald Foster , Richard Holly , Jane Gross , Janet Johnston , Andrew Nelson , Stacey Dillon , Angela Hammond
- 专利权人: ZymoGenetics, Inc.
- 当前专利权人: ZymoGenetics, Inc.
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07K16/24 ; C12P21/04
摘要:
Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.
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