发明申请
- 专利标题： REGULATABLE OR CONDITIONAL EXPRESSION SYSTEMS
- 专利标题（中）： 可管理或条件表达系统
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申请号： US11466797申请日： 2006-08-24
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公开(公告)号： US20070054872A1公开(公告)日： 2007-03-08
- 发明人: Thomas Reppen , David Lewis
- 申请人： Thomas Reppen , David Lewis
- 申请人地址： US WI Madison
- 专利权人： Mirus Bio Corporation
- 当前专利权人： Mirus Bio Corporation
- 当前专利权人地址： US WI Madison
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; C07H21/02
摘要：
Endogenous gene regulation mechanisms together with microRNAs expressed in many organisms can be used to provide regulated or conditional expression of transgenes by placing an appropriate sequence, a microRNA binding site, within the transcribed gene. This microRNA-dependent transcription regulation can be further regulated using microRNA inhibitors.