发明申请
US20070071753A1 Diagnostics and therapeutics for diseases associated with g protein-coupled receptor 85 (gpr85)
审中-公开
与g蛋白偶联受体85(gpr85)相关疾病的诊断和治疗
- 专利标题: Diagnostics and therapeutics for diseases associated with g protein-coupled receptor 85 (gpr85)
- 专利标题(中): 与g蛋白偶联受体85(gpr85)相关疾病的诊断和治疗
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申请号: US10576792申请日: 2004-10-19
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公开(公告)号: US20070071753A1公开(公告)日: 2007-03-29
- 发明人: Stefan Golz , Ulf Bruggemeier , Andreas Geerts , Holger Summer
- 申请人: Stefan Golz , Ulf Bruggemeier , Andreas Geerts , Holger Summer
- 申请人地址: DE Leverkusen 51368
- 专利权人: BAYER HEALTHCARE AG
- 当前专利权人: BAYER HEALTHCARE AG
- 当前专利权人地址: DE Leverkusen 51368
- 优先权: EP03025071.6 20031031
- 国际申请: PCT/EP04/11808 WO 20041019
- 主分类号: A61K48/00
- IPC分类号: A61K48/00 ; A61K38/55 ; G01N33/567 ; G01N33/574 ; A61K39/395
摘要:
The invention provides a human GPR85 which is associated with the cardiovascular disorders, hematological disorders, inflammatory diseases, metabolic diseases, neurological disorders, urological disorders, respiratory diseases, cancer disorders and reproduction disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular disorders, hematological disorders, inflammatory diseases, metabolic diseases, neurological disorders, urological disorders, respiratory diseases, cancer disorders and reproduction disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of GPR85 as well as pharmaceutical compositions comprising such compounds.
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