发明申请
- 专利标题: Hydrogel balloon prosthesis for nucleus pulposus
- 专利标题(中): 水髓球囊假体为髓核
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申请号: US11510747申请日: 2006-08-25
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公开(公告)号: US20070073402A1公开(公告)日: 2007-03-29
- 发明人: Edward Vresilovic , Michele Marcolongo , Anthony Lowman , Alastair Clemow , Michael Keane
- 申请人: Edward Vresilovic , Michele Marcolongo , Anthony Lowman , Alastair Clemow , Michael Keane
- 主分类号: A61F2/44
- IPC分类号: A61F2/44 ; B29C41/14
摘要:
A prosthesis for replacing or supplementing a nucleus pulposus of an intervertebral disk is an expandable container having flexible walls, the container being adapted to be inserted into a central cavity of an intervertebral disk through a narrow cannula, and the flexible walls are made from a biocompatible hydrogel. A preferred hydrogel is a cryogel formed from an aqueous solution of poly(vinyl alcohol) and poly(vinyl pyrrolidone). The prosthesis may be prepared by dip-coating a mandrel with an aqueous solution of a hydrogel-forming polymer or mixture of such polymers, gelling the coated solution by chilling, and subjecting the gelled coating to a series of repeated freeze-thaw treatments. In use, the prosthesis is inserted into a central cavity of an intervertebral disk and filled with biocompatible material, e.g., a biocompatible liquid, a biocompatible polymer, and a biocompatible hydrogel, particularly a thermogelling hydrogel.
公开/授权文献
- US08287595B2 Hydrogel balloon prosthesis for nucleus pulposus 公开/授权日:2012-10-16