发明申请
- 专利标题： Fused heterocyclic compounds useful as kinase modulators
- 专利标题（中）： 用作激酶调节剂的稠合杂环化合物
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申请号： US11524996申请日： 2006-09-21
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公开(公告)号： US20070078136A1公开(公告)日： 2007-04-05
- 发明人: Wayne Vaccaro , Zhong Chen , Dharmpal Dodd , Tram Huynh , James Lin , Chunjian Liu , Christopher Mussari , John Tokarski , David Tortolani , Stephen Wrobleski
- 申请人： Wayne Vaccaro , Zhong Chen , Dharmpal Dodd , Tram Huynh , James Lin , Chunjian Liu , Christopher Mussari , John Tokarski , David Tortolani , Stephen Wrobleski
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/53 ; A61K31/503
摘要：
Compounds having the formula (1), and enantiomers, and diastereomers, pharmaceutically-acceptable salts, thereof, are usefuil as kinase modulators, including MK2 modulation, wherein one of E and F is a nitrogen atom and the other of E and F is a carbon atom, Z is N or CR3, and R1, R2, R3, X and Y are as defined herein.