Invention Application
US20070078372A1 Iontophoresis Drug Delivery Formulation Providing Acceptable Sensation and Dermal Anesthesia
审中-公开
离子导入药物递送配方提供可接受的感觉和皮肤麻醉
- Patent Title: Iontophoresis Drug Delivery Formulation Providing Acceptable Sensation and Dermal Anesthesia
- Patent Title (中): 离子导入药物递送配方提供可接受的感觉和皮肤麻醉
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Application No.: US11537141Application Date: 2006-09-29
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Publication No.: US20070078372A1Publication Date: 2007-04-05
- Inventor: Vilambi Reddy , Preston Keusch
- Applicant: Vilambi Reddy , Preston Keusch
- Applicant Address: US NJ Fair Lawn
- Assignee: Vyteris, Inc.
- Current Assignee: Vyteris, Inc.
- Current Assignee Address: US NJ Fair Lawn
- Main IPC: A61N1/30
- IPC: A61N1/30

Abstract:
A shelf-stable electrically assisted transdermal drug delivery system for highly effective electrotransport of an anesthetic and a vasoconstrictor producing clinically acceptable dermal anesthesia and sensation is provided. In certain embodiments the anesthetic includes lidocaine and the vasoconstrictor includes epinephrine. Medicament delivery is affected to provide dermal anesthesia with little or no sensation during delivery, as measured by a variety of indicator tests. Methods of producing dermal anesthesia in patients are also provided.
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