A processor core and method for managing branch misprediction in an out-of-order processor pipeline. In one embodiment, the pipeline of the processor core includes a front-end instruction fetch portion, a back-end instruction execution portion, and pipeline control logic. Operation of the instruction fetch portion is decoupled from operation of the instruction execution portion. Following detection of a control transfer misprediction, operation of the instruction fetch portion is halted and instructions residing in the instruction fetch portion are invalidated. When the instruction associated with the misprediction reaches a selected pipeline stage, instructions residing: in the instruction execution portion of the pipeline are invalidated and the flow of instructions from the instruction fetch portion to the instruction execution portion of the processor pipeline is restarted. A mispredict instruction identification checker and instruction identification tags are used to determine if a control transfer instruction is permitted to redirect instruction fetching.