发明申请
US20070110833A1 Composition comprising the alcohol compound isolated from the extract of cucurbitaceae family plant having anti-adipogenic and anti-obesity activity
审中-公开
包含从具有抗脂肪生成和抗肥胖活性的葫芦科家族植物提取物中分离的醇化合物的组合物
- 专利标题: Composition comprising the alcohol compound isolated from the extract of cucurbitaceae family plant having anti-adipogenic and anti-obesity activity
- 专利标题(中): 包含从具有抗脂肪生成和抗肥胖活性的葫芦科家族植物提取物中分离的醇化合物的组合物
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申请号: US10581575申请日: 2004-12-03
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公开(公告)号: US20070110833A1公开(公告)日: 2007-05-17
- 发明人: Mi Jin , Jae Ryu , Hyoun Choi , Hyun Jung , Kyoung Park , Sun Kim
- 申请人: Mi Jin , Jae Ryu , Hyoun Choi , Hyun Jung , Kyoung Park , Sun Kim
- 优先权: KR10-2003-0087280 20031203
- 国际申请: PCT/KR04/03168 WO 20041203
- 主分类号: A61K36/42
- IPC分类号: A61K36/42
摘要:
The present invention is related to an extract of Cucurbitaceae family plant or the purified extract isolated therefrom having anti-adipogenic and anti-obesity activity, and a composition comprising the same. The extract of Cucurbitaceae family plant of the present invention showed potent reducing activity of body weight, decreasing effect on the blood triglyceride and cholesterol level, activating activity of PPAR α and δ, reducing activity of the gene expression of stearoyl-CoA desaturase, and preventing activity from the adipogenesis of precursor fat cells with no toxicity, therefore, those extract can be useful in treating or preventing obesity and adipogenesis-involved diseases as a medicine or health care food.