Provided are an interface circuit and a signal clamping circuit using a level-down shifter. The interface circuit includes the level-down shifter between a first power circuit driven by a first power and a second power circuit driven by a second power. The level-down shifter converts an output of the first power circuit that has a voltage level of the first power into an output of a voltage level of the second power. The level-down shifter includes a first circuit unit, a second circuit unit, a third circuit unit, and a fourth circuit unit. The first circuit unit is driven by the first power and receives the output of the first power circuit. The second circuit unit is driven by the second power and receives the output of the first power circuit. The third circuit unit is driven by the second power and receives the output of the first power circuit. The fourth circuit unit is driven by the second power, receives an output of the third circuit unit, and is connected to an output of the second circuit unit.